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Background Interleukin-22 (IL-22) is a member of the IL-10 regulatory cytokine family
The phosphorylation of LRRK2 at S935 has been implicated in modulating its kinase activity and may contribute to the pathogenesis of Parkinson's disease and other LRRK2-related disorders
and its activation is associated with the induction of apoptotic and necrotic cell death
where it plays a crucial role in mediating membrane permeability
IL-33 Full Length Protein, Human Cytokine & Cytokine Receptor Background Interleukin-22 (IL-22) is aProduct Specification Species Human Synonyms Interleukin 33,IL 33,Interleukin 1 family member 11 (IL 1F11),Nuclear factor from high endothelial venules (NF HEV), Accession O95760 Amino Acid Sequence Met1 Thr270, with N terminal His Tag Expression System E. coli Molecular Weight 33 kDa (Reducing) Purity >90% by SDS PAGE. Endotoxin <1EU g Conjugation Unconjugated Tag His Tag Storage Buffer 20mM Tris, 500mM L Arginine, 1mM DTT, pH8. 0 Reconstitution