induces UCP2-dependent mitochondrial rewiring that attenuates the generation of reactive oxygen species and preserves the integrity of Krebs cycle required for persistent production of itaconate and subsequent GATA3-dependent differentiation of inflammation-resolving alternatively activated macrophages
The cell type that secretes IL-4 to induce Th0 cell differentiation has not yet been identified
tumor growth
Other OSM-mediated activities reported to date include: stimulation of plasminogen activator activity in cultured bovine aortic endothelial cells
ANDR(LBD) Protein, Human Molecular Biology Kits induces UCP2-dependent mitochondrial rewiring thatProduct Specification Species Human Synonyms DHTR, NR3C4, AR Accession P10275 1 Amino Acid Sequence D551 T919N terminal 8x His and SUMO tag, C terminal Myc tag Expression System E. coli Molecular Weight 56. 5 kDa Purity >75% by SDS PAGE Conjugation Unconjugated Tag His Tag, SUMO, Myc Physical Appearance Liquid Storage Buffer 25mM Hepes, 150 mM NaCl, 2 mM DTT, 10 M DHT, 5% glycerol, pH7. 5 Stability & Storage Stable for 12 months upon stored at 80 from